HIGHER: Clementia Pharmaceuticals (CMTA), up 6% after reporting Phase 2B data of Palovarotene for treatment of patients with fibrodysplasia ossificans progressiva, or FOP… Cara Therapeutics (CARA), up 18% after it licensed worldwide rights, except in the U.S., Japan and South Korea, to commercialize Korsuva injection for the treatment of chronic kidney disease-associated pruritus in dialysis patients to a joint company of Vifor Pharma Group and Fresenius Medical Care (FMS)… American Equity Investment Life (AEL), up 8% after confirming reports that it is in preliminary discussions regarding a potential transaction. UP AFTER EARNINGS: Tiffany (TIF), up 15%… Lowe’s (LOW), up 5.5%… Ralph Lauren (RL), up 5%. DOWN AFTER EARNINGS: Target (TGT), down 6%…. HP Enterprise (HPE), down 4%… Red Robin (RRGB), down 20%. ALSO LOWER: Shake Shack (SHAK), down 2.5% after the stock was downgraded to Neutral from Buy at Longbow.