Futures for the Dow Jones Industrials ducked back 91 points, or 0.3%, to 34,522.
Futures for the S&P 500 dropped 26.75 points, or 0.6%, to 4,456.75.
Futures for the NASDAQ Composite Index swooned 152.5 points, or 1.1%, to 14,174.
Later this week, the first-quarter earnings season will hit its stride, with JPMorgan Chase and Delta set to report results on Wednesday morning.
The fight against inflation is likely to be a market driver this week. Investors will get a look at fresh data, with the consumer price index for March due out on Tuesday and the producer price index following on Wednesday.
Cleveland Federal Reserve President Loretta Mester told the media on Sunday that she still believes the Fed can get inflation under control.
In Asia, the Nikkei 225 in Japan docked 0.6% Friday, while in Hong Kong, the Hang Seng fell 3%.
Oil prices tumbled $4.46 to $93.80 U.S. a barrel.
Gold prices $16.10 to $1,961.70 U.S.