Quantum-Si incorporated (NASDAQ:QSI) Q1 2024 Earnings Call Transcript May 9, 2024
Quantum-Si incorporated isn’t one of the 30 most popular stocks among hedge funds at the end of the third quarter (see the details here).
Operator: Ladies and gentlemen, thank you for standing by. Welcome to the Quantum-Si First Quarter 2024 Earnings Call. At this time, all participants are in a listen-only mode. After the speaker’s presentation, there will be a question and answer session. [Operator Instructions]. Please be advice that today’s is being recorded. I would now like to turn the conference over to Katherine Atkinson from Quantum-Si. Katherine, please go ahead.
Katherine Atkinson: Good afternoon, everyone. Thank you for joining us. Earlier today, Quantum-Si released financial results for the first quarter ended March 31, 2024. The copy of the press release is available on the company’s website. Joining me today are Jeff Hawkins, President and Chief Executive Officer and Jeff Keyes, Chief Financial Officer. Before we begin, I would like to remind you that management will be making certain forward-looking statements within the meaning of Federal Securities laws. These statements involve material risks and uncertainties that could cause actual results or events to materially differ from those anticipated. Additional information regarding these risks and uncertainties appears in the section entitled Forward-Looking Statements of our Press Release.
For a more complete list and description of risk factors, please see the company’s filings made with the Securities and Exchange Commission. This conference call contains time-sensitive information that is accurate only as of the live broadcast today, May 9, 2024, except as required by law, the company disclaims any intention or obligation to update or revise any forward-looking statements. During this call, we will also be referring to certain financial measures that are not prepared in accordance with U.S., Generally Accepted Accounting Principle or GAAP. A reconciliation of these non-GAAP financial measures to the most directly comparable GAAP financial measures is included in the press release filed earlier today. With that, I will turn the call over to Jeff Hawkins.
Jeff Hawkins: Good afternoon, everyone, and thank you for joining us. In today’s call, we will provide a business update, present our first quarter of 2024 financial results, and provide an outlook for the remainder of 2024. We will then open the line for questions. As a reminder, the goal of Quantum-SI is to bring next-generation protein sequencing to every lab everywhere. Our proprietary technology delivers deeper, unbiased proteomics insights that we believe will accelerate scientific research, enable the discovery of new biomarkers, and ultimately power the development of new therapies and diagnostic tests that will positively impact human health. With the full launch of Platinum now underway, I wanted to take this opportunity to share our corporate priorities for 2024.
These priorities build upon what we have accomplished in 2023 and will guide our execution throughout the year. Our corporate priorities for 2024 are as follows. Accelerate commercial adoption, deliver on our innovation roadmap, and preserve financial strengths. With those priorities in mind, I would now like to provide an update on our progress during the first quarter, as well as provide an updated outlook for 2024. Our first corporate priority is to accelerate commercial adoption. As I discussed on our last earnings call, we were finalizing our commercial readiness to support our full commercial launch. The preparations included training of the current and new members of our direct sales force and training of our distributor network. The preparations also included the launch and initial rollout of the version 2 sequencing kit to customers, which we began executing on in early February.
As of today, all customers have successfully migrated to the version 2 sequencing kit. Based on all of these items being complete, I am pleased to announce that we have moved into the full commercial launch of Platinum as of the end of March, 2024. Going forward, we expect to have steady quarter-over-quarter revenue growth as we progress through the remainder of 2024. We will continue to closely monitor our commercial performance and customer success rates and leverage that data to execute on a thoughtful scale up of our commercial infrastructure, both direct and distribution throughout 2024. In addition to gathering routine customer feedback, we will continue to work closely with key opinion leaders and early adopters of our technology to help define and develop future applications for our technology.
As a reminder, our commercial strategy involves a mix of direct sales and distribution partners. In the U.S. market, we are currently operating with a direct sales and service model. In EMEA, our initial focus is the European market where we will use a mix of direct and distribution approaches. In addition, we have a distributor partner in Japan which we expect will serve as our strategic entry point into the broader APAC market. At the end of the first quarter, our direct commercial team, which consists of sales, marketing, service, and support personnel, encompassed approximately 24 individuals based in the United States and Western Europe. Customer interest in our uniquely differentiated technology has always been strong. From our initial launch in December of 2022 until now, we have observed consistent growth in our sales funnel in terms of the number of leads generated every month.
As we move forward with our full launch, the focus will be conversion of these leads into instrument placements and revenue. Our current commercial team size is in line with our expectations to support the early phases of the full commercial launch, and we will be closely monitoring a variety of commercial metrics as we look to shape and grow our team and approach going forward. From a market segment perspective, our customers to date have largely been academic research labs. In the first quarter, that changed in a positive way. We are pleased to report that we secured our first customers in both the government and pharma market segments. These first two success stories underpin a broader interest we are seeing emerge in these two market segments, in addition to biotech and other commercial applications.
We continue to believe academic research labs will remain a key customer for us going forward, but are pleased to see customers in these additional market segments adopting our technology as well. From an application standpoint, one application we are seeing increasing interest in is barcoding. For customers who need to generate and characterize large numbers of proteins, protein barcodes can be used to streamline screening and selection of proteins with the desired characteristics. Barcoding applications could potentially span multiple market segments, including biomedical research, pharma, biotech, and industrial. For these customers, Platinum offers a simple, cost-effective, and highly specific way to screen hundreds of proteins at once.
While adoption of our technology is in the early stages in pharma, biotech, and government labs, it does highlight that with growing market awareness and an ever-increasing set of capabilities, our technology addresses an unmet need we believe will be of interest to customers across the broad range of market segments and lab types. On a macro basis, we closely monitor this information and themes being shared by companies across the broader life sciences market regarding sales cycles and capital sales process. Early evidence of our sales cycle indicates that it is approximately a three to four month process, with a slightly longer sales cycle in some segments, as those customers may require a hands-on evaluation of our technology before making a buying decision.
In general, we expect a sales cycle trend of three to four months to continue into the future. Another theme in the broader market has been challenges securing capital budgets in general and within the market in China specifically. To-date, we have not seen these issues affect us given the price point of our Platinum device and the value that technology offers versus competitive instrumentation. As a reminder, our Platinum instrument has a current list price of $85,000, whereas many of the other instrument offerings in our space carry list prices ranging from $500,000 up to $1 million or more. With respect to China, we do not currently sell Platinum in that market, so we are not exposed to any of the headwinds being discussed by other companies in the broader life science market.
With the full commercial launch underway, we are laser focused on our commercial execution to ensure consistent quarter-over-quarter growth. We will closely monitor commercial success metrics and look to expand our commercial footprint in a physically responsible way while ensuring all our customers receive the highest level of service and support. As we have said before, our goal is not simply to place instruments, it is to secure customers who will utilize our technology to advance their research for years to come. As this process evolves, we will be nimble and adjust our approach to maximize our revenue growth while ensuring customer success. Our second priority is to deliver on our innovation roadmap. In February, we launched our version 2 sequencing kit, which includes the introduction of a new amino acid recognizer, high reproducibility across runs, and an approximately three-fold reduction in cost per amino acid.
I am pleased to report that we have successfully transitioned all our existing customers to the version 2 kit. Overall, the customer feedback for the version 2 kit has been very positive. Last week, we announced the release of a new version of our Platinum analysis software. This new version of software offers customers an average of a 55% increase in the number of peptide alignments, a 9% increase in the precision of identifying unknown proteins present in a sample, and a 70% reduction in primary analysis time from 85 minutes to 25 minutes. As part of the Analysis Software launch, we also shared some details about our proprietary kinetic model and kinetic database, made up today of nearly 2 million parameters. The ability to continuously train the kinetic model on generated sequencing data represents a significant opportunity to unlock even deeper insights from our next generation protein sequencing technology, further building upon the improvements we expect to continue to make to the sequencing chemistry.
Turning now to our version 3 kit, our product development team is fully engaged in this program and we expect to deliver this updated kit to our customers by the end of Q3 2024 as previously communicated. It is still too early to discuss full details of this latest kit update, but current development results are promising and we are expecting a very meaningful performance improvement over the version 2 kit. The level of innovation happening every day across our R&D teams is exciting to get to see. Equally important to our long-term success is the significance strives we have made in terms of project planning and execution. Delivering products our customers can use every day is the goal of our innovation pipeline, whether that be a new sequencing kit, new software or a new instrument.
Looking back at the version 2 kit project and now more recently the version 3 kit project, it is impressive to see our R&D team build plans and execute them in such close alignment with the target set out at the start of the programs. It is this level of planning and execution rigor that is critical to reliably delivering on a continuous flow of new products to customers. I’m confident we have that foundation in place and I’m personally grateful for the work our R&D teams are doing every day to advance the field of proteomics with next generation protein sequencing. Finally, we attended the U.S. Human Proteome Organization conference in March where a Quantum-SI customer gave an oral presentation regarding their use of Platinum for PTM detection and a second customer presented a poster describing their use of Platinum to develop alternative library prep applications for next generation protein sequencing.
Furthermore, in late February, Dr. Chris Mason presented a webinar about using Next-Generation Protein Sequencing to characterize extremophiles, historically difficult and understudied set of organisms that naturally exist in nature and are of interest in various industrial applications. We expect that customers will continue to present their work at industry conferences throughout 2024, further increasing awareness of the benefits of Platinum. Our third priority is to preserve financial strength. As we state on each of our calls, we remain committed to continuously improving our fiscal discipline. Now that we have the first quarter of activity completed, the results are becoming clear. We have reduced our overall spend year-over-year while improving our ability to deliver new products to the market, all while funding our commercial operations ramp up.
Jeff will go into more details on this, but we believe these results are excellent and it shows how focused we are in utilizing our capital in the most effective way. We are confident that we are appropriately balancing the need to preserve capital with our goal to maximize commercial adoption of platinum and deliver a steady cadence of new products to customers. Delivering on these two goals represents a significant strategic advantage that will be the foundation of our growth for years to come. I will now turn the call over to Jeff Keyes to review our financial results. Jeff.
Jeff Keyes: Thank you, Jeff. Now let’s discuss the details of our first quarter of 2024 financial results. Revenue in the first quarter of 2024 was $457,000, which consisted of revenue from our Platinum instrument, consumable kits and related services. Gross profit was $269,000 and gross margin was 59%. As I have stated before, our gross margin percentage will be somewhat variable in the near future as we work through our initial stages of commercialization and will also be impacted by the timing and mix to instruments versus consumable sales. Our margin will also be impacted in the near term by acquisition costs and any accounting adjustments to underlying inventory that dates back to the pre-commercial stage of Quantum-SI.
As we are still working through these items, we have not provided a margin percentage guidance for 2024, but what I can say is the margin mix for the first quarter of 2024 includes approximately a 10% benefit for inventory utilized in the first quarter that were carried at low or no value that dates back to prior to our initial commercialization. We expect more of these variances that will work through into our margin over the course of the year both positive and negative, and I will point them out as these things evolved. GAAP total operating expenses in the first quarter of 2024 were $23.6 million compared to $29.3 million in the first quarter of 2023, while adjusted operating expenses were $21.9 million for the first quarter of 2024, compared to $24.6 million for the first quarter of 2023.
As we alluded to in our press release today, the year-over-year reduction in operating expenses was the result of several initiatives we put in place in 2023 to maximize our capital efficiency, including our R&D realignment efforts, while at the same time delivering a steady cadence of R&D enhancements to our customers. Specifically, this has resulted in lower spend in R&D by $6.1 million and effectively swapping G&A dollars to fund commercial operations, increasing overall SG&A by only $350,000. Net loss for the first quarter of 2024 was $19.5 million compared to $23.6 million in the first quarter of 2023, a decrease of $4.1 million. The decrease in net loss was primarily related to the operating expense reduction previously discussed, partially offset by changes in dividend income and unrealized gains on marketable securities.
Adjusted EBITDA for the first quarter of 2024 was negative $20.5 million compared to negative $23.7 million in the first quarter of 2023, an improvement of $3.2 million. This improvement was primarily related to the aforementioned reduction in operating expenses, primarily in R&D related costs. Near the end of 2023, we made some structural changes to our investment holdings make up to maximize yield while minimizing risk. These changes, along with the impact of rate increases, produced dividend and interest income of $3.6 million in the first quarter of 2024, compared to $2.2 million in the first quarter of 2023, an increase of $1.4 million. As of March 31st, 2024, we had $235.4 million in cash and cash equivalents and investments in marketable securities.
We are also reaffirming our 2024 financial guidance, which includes revenues to range between $3.7 million and $4.2 million, adjusted operating expenses to be less than $103 million, and net cash usage less than $100 million. Finally, we still expect that our existing cash and cash equivalents and investments in marketable securities will provide runway into 2026. Now I will turn the call over to the operator to open the line for questions.
Operator: Thank you. At this time, we will conduct the question and answer session. [Operator Instructions] Our first question comes from Swayampakula Ramakanth with HCW. Please go ahead with your question.
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